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By April 30, 2020 No Comments

Importance of Heterocyclic molecules

The drugs used in human medicine cover the whole range of chemical structure types, but majorities are heterocyclic molecules. Of the top 10 best – selling (prescription) drugs by value in the year June 2006 – June 2007, seven were heterocycles: atorvastatin (Lipitor; $13.5bn; a statin for cholesterol reduction); esomeprazole (Nexium; $6.9bn; a proton – pump inhibitor for reduction of gastric acid); clopidogrel (Plavix; $5.8bn; an anti – platelet agent to prevent blood clots); olenzapine (Zyprexa; $4.9bn; an anti – schizophrenic); risperidone (Risperdal; $4.8bn; an anti – schizophrenic); amlodipine (Norvasc; $4.5bn; an anti – hypertensive agent); quetiapine (Seroquel; $4.2bn; for treatment of schizophrenia and bipolar disorder).

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